A man and a woman walking for exercise

Healthy Diet and Lifestyle Study 2

The Healthy Diet and Lifestyle Study II looks at whether changes in dietary habits, along with a regular physical activity plan, can affect the amount of fat stored in your abdomen and the rest of the body to reduce disease risk. This study aims to test the difference between two approaches to energy (calorie) restriction, assess participants' adherence to the diets, and whether either diet helps to reduce the fat around the internal abdominal organs. It also looks at the effect of these diets on the gut microbiome.

Participants will be randomly assigned to one of two energy (calorie) restriction plans, both based on the health-promoting Mediterranean-type diet, and asked to follow their diet for 24 weeks under the counseling of a dietitian. Both groups will be asked to follow an exercise plan and use the study’s mobile phone app to take photos of their foods on specific days. Body measurements, including advanced imaging of body fat, will be taken at three time points during the 24-week regimen and six months after study completion by trained clinic staff.

For more information about the study, call (808) 237-3901 or email This email address is being protected from spambots. You need JavaScript enabled to view it..

• Oʻahu resident
• East Asian (Japanese, Chinese, or Korean), European White, Native Hawaiian, Pacific Islander, or Filipino ancestry
• 35 to 69 years old
• Slightly or more than slightly overweight
• Have not smoked in the last 2 years
• Would like to improve eating and exercise habits and have the commitment to follow the diet and physical activity regimen for 24 weeks

• No cost to join
• Menu planning by a dietitian
• Latest science to help improve health
• Compensation for time and travel